ABCG1是ABC转运蛋白家族中的成员，是位于组织浆膜中的单体转运蛋白，多分布于肝、小肠、胎盘、脂肪和脾.主要用于脂质/脂蛋白代谢与动脉粥样硬化方面的研究。
    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette （ABC） transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies （ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White）. This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified.